American Restaurants in Charleston, MO

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1. The Glenn

The Glenn

2460 S Highway 105, Charleston, MO 63834

CLOSED NOW:5:00 pm - 10:00 pm

2. McDonald's

McDonald's

2071 S Main St, Charleston, MO 63834

CLOSED NOW:5:00 am - 11:00 pm

From Business: McDonald’s USA, LLC, serves a variety of menu options made with quality ingredients to millions of customers every day. Ninety-five percent of McDonald’s approximately 13,500…

3. Huddle House

Huddle House

2460 E Highway 60, Charleston, MO 63834

OPEN 24 HOURS

From Business: We're Always Cookin' There's something about a freshly made meal, prepared just for you. Maybe it's a waffle sundae to celebrate the day you get your braces off, or a plate…

4. Wally's Homestyle Cooking

Wally's Homestyle Cooking

100 Beasley Park Rd, Charleston, MO 63834

CLOSED NOW:6:00 am - 11:00 pm
Amenities:
Wheelchair accessible

6. Willie Mae's Wings & Things

Willie Mae's Wings & Things

902 S Main St, Charleston, MO 63834

CLOSED NOW:11:00 am - 7:00 pm
Amenities:
Wheelchair accessible

8. Lambert's Cafe

Lambert's Cafe

2305 E Malone Ave, Sikeston, MO 63801

CLOSED NOW:10:30 am - 9:00 pm

"Visited the restaurant June 9. Had a great waiter. She was special and very helpful. Fast service and great food."

YP
83 Years
in Business
Amenities:
Good for familiesWheelchair accessibleGood for groups

9. Cheers Bar & Grill

Cheers Bar & Grill

1212 Linn St, Sikeston, MO 63801

OPEN 24 HOURS

From Business: Local restaurant serving wide variety of food, from hamburger to seafood, cajun to steaks. Been in business since 1990. Full line of bar products such as beer, liquor and wine.…

YP
35 Years
in Business
Amenities:
Wheelchair accessible

10. Depot BBQ

Depot BBQ

111 S Lincoln St, East Prairie, MO 63845

CLOSED NOW:4:30 pm - 8:00 pm
YP
24 Years
in Business
Amenities:
Wheelchair accessible

11. Ruby Tuesday

Ruby Tuesday

2612 E Malone Ave, Sikeston, MO 63801

CLOSED NOW:11:00 am - 11:00 pm
Amenities:
Serves alcohol

13. Merick's Sandwich Shop

Merick's Sandwich Shop

901 E Malone Ave, Sikeston, MO 63801

CLOSED NOW:10:00 am - 8:00 pm

15. Susie's Bake Shop & Restaurant

Susie's Bake Shop & Restaurant

112 E Center St, Sikeston, MO 63801

CLOSED NOW:8:00 am - 5:00 pm
YP
28 Years
in Business

16. Applebee's

Applebee's

1260 S Main St, Sikeston, MO 63801

OPEN NOW:11:00 am - 12:00 am

"I absolutely love Applebee's! I am a single man and I come in alot. Everytime I come in I seem to get kasey as my server. She is an awesome waitress no matter how busy she is…"

YP
45 Years
in Business
Amenities:
Serves alcohol

17. Jeremiah's Restaurant & Lounge

Jeremiah's Restaurant & Lounge

102 N Kingshighway St, Sikeston, MO 63801

OPEN NOW:4:00 pm - 1:00 am
YP
34 Years
in Business
Amenities:
Wheelchair accessible

21. Sonic Drive-In

Sonic Drive-In

201 Prairie Dr, East Prairie, MO 63845

CLOSED NOW:6:00 am - 9:00 pm

From Business: SONIC Drive-Ins and drive-thrus are open! Enjoy SONIC Drive-In from the comfort and safety of your car. Plus, the SONIC App offers contactless ordering and payment using your…

YP
72 Years
in Business

22. Burger King

Burger King

99 Matthews Ln, Sikeston, MO 63801

CLOSED NOW:6:00 am - 11:00 pm

From Business: There's a Burger King® restaurant near you at 99 Matthews Lane. Visit us or call for more information. Every day, more than 11 million guests visit over 13,000 Burger King®…

23. Wendy's

Wendy's

1701 E Malone Ave, Sikeston, MO 63801

CLOSED NOW:6:30 am - 11:00 pm

"Great place to eat. They are very fast if you know what you want (hint to the people standing in line in front of me). Drive thru has to be the fastest in town."

24. Bo's Breakfast and Bar-B-Q

Bo's Breakfast and Bar-B-Q

1609 E Malone Ave, Sikeston, MO 63801

CLOSED NOW:6:00 am - 8:00 pm

From Business: Bo's Breakfast and Bar-B-Q provides breakfast and BBQ to the Sikeston, MO area.

YP
54 Years
in Business

27. HomeTown Buffet

HomeTown Buffet

115 E Pine St, East Prairie, MO 63845

CLOSED NOW:6:00 am - 8:00 pm

28. Hardee's

Hardee's

1105 S Main St, Sikeston, MO 63801

CLOSED NOW:6:00 am - 9:00 pm

From Business: Hungry and craving a tasty, breakfast or burger place near you? From fluffy Made From Scratch™ Biscuits to crispy bacon on our classic breakfast platter, to charbroiled burgers…

30. Grecian Steak House

Grecian Steak House

531 Greer Ave, Sikeston, MO 63801

CLOSED NOW:11:00 am - 9:00 pm

"Went to this restaurant yesterday. I could not believe that the hostess actually asked if we preferred Smoking or Non-Smoking. In this day and age, how can a …"

YP
48 Years
in Business
Amenities:
Serves alcoholWheelchair accessible

We found 36 results for American Restaurants in or near Charleston, MO.They also appear in other related business categories including American Restaurants, Hamburgers & Hot Dogs, and Fast Food Restaurants. 6 of these businesses have an A/A+ BBB rating. 10 of the rated businesses have 4+ star ratings.