From Business: Located directly off I-55, Drury Suites Cape Girardeau is the perfect stop for business or leisure travelers. At the heart of Cape Girardeau, the hotel is just minutes away…

From Business: The Pear Tree Inn Sikeston is conveniently located off I-55 in Sikeston near shopping and dining at local legend Lambert’s Café. Sikeston is halfway between St. Louis and…

From Business: Everyone needs a place to lay their weary head. For travelers visiting Cape Girardeau, Neumeyer's Bed and Breakfast is an excellent choice for rest and rejuvenation. Well-known…

From Business: Bellevue Bed and Breakfast is an excellent choice for travelers visiting Cape Girardeau, offering a romantic environment alongside many helpful amenities designed to enhance…

From Business: See why so many travelers make Comfort Inn & Suites Sikeston their hotel of choice when visiting Sikeston. Providing an ideal mix of value, comfort and convenience, it offers a…

"It was my first time staying at a Best Western and I enjoyed it. I was suprised to see how much space we had in our room. But, it was a good amount of space for the cost of the…"

From Business: IHG Rewards Club Members: Get better savings with YOUR RATE. Book hotels direct at candlewoodsuites.com for our lowest rates. You won't find these anywhere else. Experience…

From Business: The Fairfield Inn and Suites is Cape Girardeau's newest property by Marriott that features a saltwater pool, fitness center and a free hot breakfast to fuel up your stay. Relax…

From Business: From our daily free hot breakfast to our nightly cookie hour, Hampton Inn Cape Girardeau I-55 East makes you feel at home. Located on the southeast corner of I-55 and William…

"One of the nicest mid-range hotels I've have stayed at. Great staff, beautiful lobby and rooms. Will be back next time."

From Business: Motel 6 Sikeston is an excellent choice for travelers visiting Sikeston, offering a budget friendly environment alongside many helpful amenities designed to enhance your stay.…

From Business: This wyndham Hotels affiliate is a all Suite property with large bedrooms and living rooms, 2 LED television in each room, located near restaurants, Sikeston Jaycee Bootheel…

From Business: Whether traveling for business or fun, Courtyard by Marriott® makes all your travels successful by providing what you need: spacious, thoughtful guest rooms and services that…

From Business: IHG Rewards Club Members: Get better savings with YOUR RATE. Book hotels direct at holidayinnexpress.com for our lowest rates. You won't find these anywhere else. Large…